With a top prize of $100,000, the Intel Science Talent Search is one of the most competitive science fair events in the country. It's a proving ground for budding scientists, and several past winners have gone on to win
Nobel Prizes,
MacArthur Fellowships, and other major awards. At this level the competition is so fierce that it's considered a real honor just to be a semifinalist. Only the most sophisticated, rigorous projects have much of a chance, and you need to get started early.