Paroxetine

Paroxetine or Paxil, drug known as an antidepressant that functions by promoting higher levels of the neurotransmitter serotonin in the brain. Low levels of serotonin are thought to be associated with depression.

Paroxetine must be prescribed by a doctor. The drug is available in tablet form and is taken orally. Patients take up to 50 mg of the drug per day in one dose, preferably in the morning. Within ten days of regular use, the drug’s concentration reaches a constant level in the bloodstream. Two to four weeks of use are necessary before the patient feels the drug’s benefits.

Common side effects of paroxetine include dizziness, tremor, nervousness, insomnia, dry mouth, nausea, constipation, diarrhea, decreased appetite, and impaired sexual function. Rarer reactions include dizziness upon rising from a seated or prone position, anxiety, urinary disorders, skin rashes, and muscle weakness.

Pregnant and nursing women should not use this drug. Patients with liver or kidney impairment, a history of seizure disorders, or manic-depressive mental illness should exercise caution when using the drug.

Paroxetine interacts harmfully with cimetidine, digoxin, monoamine oxidase inhibitors, warfarin, and tryptophan. Because tryptophan also occurs naturally in many foods (including turkey and milk), paroxetine patients must carefully regulate their diets. Alcohol should not be consumed by patients using paroxetine.

Brand Name: Paxil