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Lesch-Nyhan syndrome

Lesch-Ny·han syn·drome [ lèsh n ən sìndrōm ]


noun 
Definition:
 
serious genetic disease: a rare recessive enzyme-deficiency disorder of male children resulting in overproduction of uric acid. It causes early cerebral palsy, developmental disorders, gout, twitching body movements, and compulsive self-mutilation by biting.

[Mid-20th century. After Michael Lesch (b. 1939), U.S. cardiologist, and William Leo Nyhan (b. 1926), U.S. pediatrician]
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