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vain, vane, or vein? Do not confuse the spelling of vain, vane, and vein, which sound similar. Vain is an adjective meaning "excessively proud," "unsuccessful," or "devoid of meaning," as in a vain man, a vain hope, vain threats; it is also used in the phrase in vain, as in trying in vain to reach them. Vane is a noun denoting a flat rotating blade or the flat part of a feather; a weather vane indicates the direction of the wind. Vein is chiefly used as a noun, denoting a blood vessel, a similar structure in a leaf or an insect's wing, a layer of ore in rock, or a streak in something such as marble, wood, or cheese.
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