1. spread of cancer: the spread of a cancer from the original tumor to other parts of the body by means of tiny clumps of cells transported by the blood or lymph
2. malignant tumor: a malignant tumor that has developed in the body as a result of the spread of cancer cells from the original tumor
[Late 16th century. Via late Latin< Greek, "removal, change" < methistanai "remove" < histanai "to place"]
