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endwise
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enervate

en·er·vate [ énnər vàyt ] (past and past participle en·er·vat·ed, present participle en·er·vat·ing, 3rd person present singular en·er·vates)


transitive verb 
Definition:
 
weaken: to weaken somebody's physical, mental, or moral vitality
I was feeling quite enervated by the strain of moving.

[Early 17th century. < Latin enervat-, past participle of enervare "extract the sinews of, weaken" < nervus "sinew"]

en·er·va·tion [ ènnər váysh'n ] noun
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