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desperado
desperate
desperation
despicable
Despina
despise
despite
despoil
despond
despondent
despot
despotic
despotism
despumate
desquamate
Dessau
dessert
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despond

de·spond [ di spónd ]


intransitive verb  (past and past participle de·spond·ed, present participle de·spond·ing, 3rd person present singular de·sponds)
Definition:
 
give up hope: to become discouraged or lose hope



noun 
Definition:
 
hopelessness: a feeling of extreme unhappiness and hopelessness
a slough of despond

[Mid-17th century. < Latin despondere "give up (your vitality)" < spondere "to promise"]

de·spond·ing·ly adverb
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