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despatch
despedida
desperado
desperate
desperation
despicable
Despina
despise
despite
despoil
despond
despondent
despot
despotic
despotism
despumate
desquamate
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despite

de·spite [ di spt ]


preposition 
Definition:
 
1. regardless of: although it might have been prevented by something
The mission blasted off today despite bad weather.

2. contrary to: indicates that something is done unexpectedly or unintentionally
She blushed deeply despite herself.

[13th century. Via Old French despit "spite" < Latin despect-, past participle of despicere (see despise)]

in despite of in spite of or notwithstanding (archaic)

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