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Despina
despise
despite
despoil
despond
despondent
despot
despotic
despotism
despumate
desquamate
Dessau
dessert
dessert wine
dessertspoon
destabilize
destalinization
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despair

de·spair [ di spér ]


noun 
Definition:
 
1. feeling of hopelessness: a profound feeling that there is no hope

2. cause of hopelessness: somebody or something that makes somebody feel hopeless or exasperated
He was the despair of his soccer coach.



intransitive verb  (past and past participle de·spaired, present participle de·spair·ing, 3rd person present singular de·spairs)
Definition:
 
lose hope: to feel that there is no hope

[14th century. Via French< Latin desperare "stop hoping" < sperare "to hope" < spes "hope"]
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