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desm-
desman
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desmosome
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desorption
despair
despairing
despatch
despedida
desperado
desperate
desperation
despicable
Despina
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despair

de·spair [ di spér ]


noun 
Definition:
 
1. feeling of hopelessness: a profound feeling that there is no hope

2. cause of hopelessness: somebody or something that makes somebody feel hopeless or exasperated
He was the despair of his soccer coach.



intransitive verb  (past and past participle de·spaired, present participle de·spair·ing, 3rd person present singular de·spairs)
Definition:
 
lose hope: to feel that there is no hope

[14th century. Via French< Latin desperare "stop hoping" < sperare "to hope" < spes "hope"]
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